The ratio of the dose of a drug that is toxic to humans compared to its minimum effective dose is called the therapeutic index
The relative safety of a medicine is quantified by the therapeutic index (TI; also known as the therapeutic ratio). The quantity of a therapeutic agent that has a therapeutic impact is compared to the amount that has a harmful effect. A range of dosages that optimum between effectiveness and toxicity, delivering the maximum therapeutic benefit without producing intolerable side-effects or toxicity, is referred to as the therapeutic window or safety window.
The therapeutic index compares the blood concentration at which a medicine has a therapeutic effect to the quantity that results in toxicity or death in animal or human trials.
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